Synthetic aspects, structural insights and pharmacological potential of pyrazole derivatives: an overview

Synthetic aspects, structural insights and pharmacological potential of pyrazole derivatives: an overview

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Abstract There is an increase in infectious diseases every year.Heterocyclic compounds have been in use as drugs sweers island for sale for a long time.Amongst many heterocyclic derivatives, the drugs containing the pyrazole core has been in limelight because of its relative ease of synthesis and excellent biological activities.Pyrazoles are aromatic compounds consisting of ring structure where two nitrogen atoms are adjacent to each other and contain three carbon atoms.Over the years pyrazoles have been explored for a variety of pharmacological applications.

Herein, this review overviews the information related to industrially important pyrazoline scaffolds and their applications, recent literature on synthesizing the pyrazole derivatives, providing an explanation for their biological activity by focusing jolly rancher lemonade stand on their structural activity relationship and hence affording ideas to design the compounds containing pyrazole scaffolds.Graphical abstract.